Demystify Gastroprotection With Antithrombotics

There’s still debate about how to limit GI bleeding risk in patients taking antithrombotics (aspirin, Eliquis, warfarin, etc).

We know that these meds increase GI bleeding risk...especially if more than 1 is needed, such as for patients with atrial fib plus a recent coronary stent. But PPIs also have risks (C. diff, etc).

In general, suggest gastroprotection for patients on an antithrombotic with a prior GI bleed...those who also need a chronic steroid or NSAID...or if 2 or more antithrombotics are necessary.