Adding topiramate to phentermine increases weight loss.
Some prescribers are writing for phentermine plus topiramate (Topamax) for weight loss.
There’s even a phentermine and extended-release topiramate combo in the pipeline called Qnexa.
Phentermine is modestly effective short-term for suppressing appetite. The antiseizure drug topiramate also decreases appetite...and possibly also inhibits lipid formation.
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