aspirin and metoclopramide (Reglan) for migraines
More physicians are prescribing aspirin and metoclopramide (Reglan) for migraines...as an alternative to sumatriptan (Imitrex).
Surprisingly, the aspirin/metoclopramide combo often works as well as oral sumatriptan.
The combination also seems to have fewer side effects. Metoclopramide tends to cause drowsiness...but sumatriptan is more likely to cause nausea...fatigue...weakness.