boxed warning about stopping Pradaxa (dabigatran), Xarelto (rivaroxaban), or Eliquis (apixaban) in atrial fib patients

July 2013

You'll see a boxed warning about stopping Pradaxa (dabigatran), Xarelto (rivaroxaban), or Eliquis (apixaban) in atrial fib patients.

Stopping these new anticoagulants...even for a few days...can quickly return patients to their risk of stroke before starting therapy.

That's because these anticoagulants are short-acting...with half-lives of about 12 hours compared to about 40 hours with warfarin.

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Table of Contents

Obesity & Weight Loss Belviq (bel-VEEK, lorcaserin) will join Qsymia and other weight loss meds in the battle of the bulge
Respiratory & Allergy Inhaled steroids are in and LONG-acting beta-agonists are out for exercise-induced bronchoconstriction
Cardiology new ezetimibe and statin combo for dyslipidemia called Liptruzet (LIP-true-zet)
Practice Pharmacists will get more involved in "transitions of care"
Ophthalmology The new combo Simbrinza (sim-BRIN-za, brinzolamide/brimonidine) will raise questions about treatments for open-angle glaucoma
Anticoagulants boxed warning about stopping Pradaxa (dabigatran), Xarelto (rivaroxaban), or Eliquis (apixaban) in atrial fib patients
Psychiatry A new desvenlafaxine extended-release will create confusion
Osteoporosis New labeling will suggest STOPPING bisphosphonates (alendronate, etc) after 3 to 5 years in patients at low fracture risk
New Drugs Many people assume FDA considers the VALUE of new drugs as part of their drug approval process
Sunscreens ask about sunscreens
NSAIDs a bigger push to avoid ORAL diclofenac