Expect a Limited Role for Basal Insulin/GLP-1 Agonist Combo Products

New combo products will raise questions about when to use basal insulin with a GLP-1 agonist for type 2 diabetes.

Combining a GLP-1 agonist (Victoza, etc) and basal insulin (Lantus, etc) may be an alternative to increasing the basal insulin dose...or adding mealtime insulin.

This "insulin-sparing" approach leads to less weight gain than a similar dose of basal insulin alone...with a similar hypoglycemia risk.

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