Double Down on Efforts to Improve Methotrexate Safety

You’ll see more emphasis on preventing errors with methotrexate...since dangerous mix-ups with this high-alert med aren’t going away.

A big issue continues to be dosing. Accidentally taking methotrexate DAILY versus WEEKLY can lead to liver damage, immunosuppression, and death.

The Institute for Safe Med Practices (ISMP) is encouraging that computer systems default to “weekly” directions for oral methotrexate Rxs...and require an indication if it’s prescribed daily.

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