Avoid Clinical Inertia in Patients With HFrEF and CKD
Few patients with chronic kidney disease (CKD) are on optimized meds for heart failure with reduced ejection fraction (HFrEF).
It’s a delicate balance. Hyperkalemia can occur with an ACEI or ARB, Entresto (sacubitril/valsartan), or an aldosterone antagonist.
Plus these meds or SGLT2 inhibitors (Farxiga, etc) can cause an initial bump in serum creatinine (SCr).