Oral antihistamines lose their effectiveness when taken chronically.

January 1

  Some people who initially get relief from their antihistamines say that their allergic symptoms return within a couple of weeks or months.

  Patients taking first generation antihistamines (Benadryl, chlorpheniramine, etc) seem to be the ones who complain of this.

  A couple of older studies suggest that chlorpheniramine loses its ability to suppress the wheal and flare reaction after chronic dosing.

Get concise advice on drug therapy, plus unlimited access to CE

Pharmacist's Letter membership benefits include:

  • 12 issues every year — what you need to know and do, right now
  • Quick, practical reference charts and tools
  • Comprehensive CE library to meet license renewal and state requirements
  • Multiple course formats including live webinars, podcasts, and CE-in-the-Letter to match your learning style
  • Plus much more!

Choose the right tier for your needs today.

Already a subscriber? Log in

Volume pricing available. Get a quote