risk of renal impairment in patients taking an ACE inhibitor or ARB, diuretic, and NSAID

Experts are reminding us of the risk of renal impairment in patients taking an ACE inhibitor or ARB, diuretic, and NSAID.

These drugs reduce renal perfusion by different mechanisms.

Combining any two of these drugs can lead to acute renal failure in susceptible patients. Combining all three is a "triple whammy."

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