whether it's okay for patients on clopidogrel (Plavix, etc) to take a PPI

June 2013

We're still getting questions about whether it's okay for patients on clopidogrel (Plavix, etc) to take a PPI...and if so, which one.

Some PPIs may decrease the antiplatelet effects of clopidogrel.

But the most reliable data suggest that there's NO increase in cardiovascular events in patients taking clopidogrel plus a PPI.

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