You should cut the dose of Glucovance in half when switching patients who are already taking glyburide and metformin separately.
Absolutely not. DON'T do it.
We can see how a rumor like this could have gotten started.
It is true that the amount of glyburide absorbed in a Glucovance tablet isn't equivalent to regular glyburide tabs. Glucovance provides slightly greater absorption, about 7% to 18% more glyburide is absorbed.