Set Expectations About PPIs for Treating GERD

You play a key role in optimizing PPIs for gastroesophageal reflux disease (GERD).

PPIs are still the mainstay for severe or frequent GERD symptoms, such as heartburn or regurgitation 2 or more times/week.

Recommend starting with a standard-dose PPI (omeprazole 20 mg, etc) once daily 30 to 60 min before the first meal of the day...since PPIs inhibit active proton pumps.

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