Don’t Consider CrCl and eGFR Interchangeable

Questions are coming up about the best way to estimate kidney function for drug dosing and decisions about med use.

Dosing recommendations based on creatinine clearance (CrCl) have been the standard since the 1970s.

But now dosing based on estimated glomerular filtration rate (eGFR) is showing up in more Rx labels (Entresto, SGLT2 inhibitors, etc).