Statins decrease the efficacy of Plavix (clopidogrel)

  Years ago, researchers used to think so.

  Some platelet studies suggested that atorvastatin or simvastatin inhibit the antiplatelet effects of clopidogrel.

  It was thought that since these statins and clopidogrel are both substrates for CYP450 3A4, that they might compete...reducing the effects of Plavix.

Get concise advice on drug therapy, plus unlimited access to CE

Pharmacist's Letter includes:

  • 12 issues every year, with brief articles about new meds and hot topics
  • 300+ CE courses, including the popular CE-in-the-Letter
  • Quick reference drug comparison charts
  • Access to the entire archive

Already a subscriber? Log in

Volume pricing available. Get a quote