Proton pump inhibitors decrease the effects of clopidogrel (Plavix).

January 1

For updated information on this topic, please see Detail-Document #250401

  Patients commonly receive a PPI when getting clopidogrel (Plavix)...to decrease the risk of GI bleeding after a coronary stent.

  In vitro tests suggest that clopidogrel doesn't inhibit platelets as well in patients taking omeprazole (Prilosec).

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