take levothyroxine FIRST THING in the morning on an empty stomach

It's important to take levothyroxine FIRST THING in the morning on an empty stomach...because absorption can be decreased by calcium, iron, fiber, and other substances.

New evidence suggests that even coffee MIGHT reduce absorption.

Tell patients to wait at least 30 minutes before eating...and 4 hours to take supplements with calcium, iron, magnesium, or aluminum. The same 4-hour wait goes for sucralfate, cholestyramine, and orlistat.

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