possible link between metformin and peripheral neuropathy

August 2009

There's new concern about a possible link between metformin and peripheral neuropathy...due to lowered vitamin B12 levels.

Up to 30% of patients on metformin have reduced B12 absorption which could eventually lead to B12 deficiency.

Severe B12 deficiency can cause anemia...and nerve damage that could be mistaken for peripheral neuropathy due to diabetes.

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