Stronger warnings about an increased risk of myopathy will limit doses of simvastatin (Zocor, etc)

April 2010

See updated FDA safety information concerning new restrictions and dose limitations for Zocor (simvastatin)

Stronger warnings about an increased risk of myopathy will limit doses of simvastatin (Zocor, etc).

Myopathy risk with simvastatin 80 mg is much higher than with lower doses...and possibly higher than with other statins.

Discourage using simvastatin 80 mg/day. Explain that going from 40 to 80 mg lowers LDL just 6% more but increases myopathy risk 6 times.

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Table of Contents

Respiratory & Allergy new controversy over treating asthma with long-acting beta-agonists (salmeterol, formoterol)
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Neurology & Pain Pennsaid, a new Rx topical diclofenac solution
Pediatrics whether CHILDREN should take fish oil supplements
Gastroenterology Which of these OTCs is NOT like the others...Maalox Advanced, Maalox Total Relief, or Pepto-Bismol
Geriatrics adjust med regimens to help avoid falls in the frail elderly
Statins Stronger warnings about an increased risk of myopathy will limit doses of simvastatin (Zocor, etc)
concerns about the safety of denture adhesives with zinc
whether cell phones, smart phones, and other electronic devices can interfere with hospital equipment
Diabetes Meds Ongoing concerns about Avandia (rosiglitazone)