NSAIDs can be a challenge in patients taking low-dose aspirin

NSAIDs can be a challenge in patients taking low-dose aspirin.

Adding an NSAID increases GI risk...and can increase cardiac risk.

NSAIDs with COX-1 activity (naproxen, ibuprofen, etc) seem to have a lower cardiovascular risk than those with more COX-2 activity (celecoxib, diclofenac, etc).

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