appropriate drug regimens for H. pylori

The clarithromycin and tetracycline shortages will bring up more questions about appropriate drug regimens for H. pylori.

Triple therapy with a PPI, clarithromycin, and amoxicillin or metronidazole is often used first-line...but usually should NOT be. Efficacy rates are falling due to increasing clarithromycin resistance.

Recommend starting with quadruple or concomitant therapy instead.

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