Watch for Ketoacidosis With Flozins
See updated FDA information (December 2015) concerning SGLT2 inhibitors (Flozins) and ketoacidosis/urinary tract infections.Colleagues will ask you whether Invokana (canagliflozin) and other SGLT2 inhibitors or "flozins" are linked to ketoacidosis.
This seems to be a flozin class effect...and has researchers scratching their heads about the mechanism.
It's different from the ketoacidosis we typically see with VERY high blood glucose. It's happening in patients with type 1 or 2 diabetes when glucose levels are near normal or only slightly elevated.