Watch for Interactions Between Amiodarone and Hep C Meds

June 2015

You'll hear reports of a potentially dangerous interaction between amiodarone and the new hep C drug, sofosbuvir (Sovaldi, Harvoni).

Combining amiodarone with sofosbuvir-containing hep C regimens may lead to serious bradycardia, cardiac arrest, and pacemaker placement.

Patients seem to be at higher risk for bradycardia if they are also on a beta-blocker or have cardiovascular or liver disease.

Get concise advice on drug therapy, plus unlimited access to CE

Pharmacist's Letter includes:

12 issues every year, with brief articles about new meds and hot topics
300+ CE courses, including the popular CE-in-the-Letter
Quick reference drug comparison charts
Access to the entire archive

Subscription Options

Already a subscriber? Log in

Volume pricing available. Get a quote

Table of Contents

Diabetes Help Choose Metformin Add-Ons Based on Their Pros and Cons
Heart Failure Don't Think of Corlanor as a Replacement for Beta-Blockers for Heart Failure
Asthma Consider Suggesting a Dry-Powder Albuterol Inhaler if an MDI Poses Problems
Constipation Don't Count on Stool Softeners to Help Opioid-Induced Constipation
Women's Health Explain When Back-Up Contraception is NOT Needed with Antibiotics
Hypertension Recommend a Beta-Blocker in CAD Patients with Hypertension
Substance Use Disorder Consider Pill Reminder Apps for Teenagers
Substance Use Disorder Be Aware Adult Beverages Now Come "Ready for Reconstitution"
Sunscreens Debunk Myths About Sunscreens
Coupons & Discounts Think Twice Before Using a Free Drug Coupon
Interactions Watch for Interactions Between Amiodarone and Hep C Meds
Days' Supply Use the Right Drops Per mL Conversion Factor to Avoid Days' Supply Issues
Infectious Diseases Recommend Coverage for Atypicals in Hospitalized Pneumonia Patients
Stroke Have a Pharmacist Respond to Acute Strokes to Help with tPA