Listen for Gliptin Patients Complaining of Severe Joint Pain

A new FDA warning will spur questions about whether gliptins (Januvia, Onglyza, etc) cause severe joint pain.

This risk seems to be a class effect of gliptins, and it's very rare...but the pain can be disabling.

We know these diabetes meds inhibit dipeptidyl peptidase-4 (DPP-4)...an enzyme that breaks down incretin hormones.

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