Expect to See Subcutaneous Methotrexate for Rheumatoid Arthritis
You'll see more methotrexate options for rheumatoid arthritis.
Oral methotrexate is still first-line for most rheumatoid arthritis patients. But it can be hard to tolerate...making it tempting to go to other DMARDs (sulfasalazine, etc) or biologics (Humira, etc) too soon.
Evidence suggests SUBCUTANEOUS methotrexate may have fewer GI side effects than oral and be more effective because it's better absorbed...especially at doses of 15 mg or more per week.