Expect Spravato to Have a Limited Role for Resistant Depression
You'll hear buzz about new Rx Spravato (sprah-VAH-toh, esketamine) nasal spray for treating adults with resistant depression.
Some experts already use low-dose IV ketamine infusions in these patients...since growing data suggest this may "jump-start" improvement.
Spravato is the active isomer of ketamine. Both block N-methyl-D-aspartate (NMDA) receptors.