Expect Spravato to Have a Limited Role for Resistant Depression

You'll hear buzz about new Rx Spravato (sprah-VAH-toh, esketamine) nasal spray for treating adults with resistant depression.

Some experts already use low-dose IV ketamine infusions in these patients...since growing data suggest this may "jump-start" improvement.

Spravato is the active isomer of ketamine. Both block N-methyl-D-aspartate (NMDA) receptors.

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