Help Patients Sniff Out Whether Azelastine Prevents COVID-19

November 2025

Questions will come up about whether to use azelastine, an antihistamine nasal spray, for prevention of COVID-19.

Azelastine nasal spray (Astepro) is a long-standing, commonly used treatment for allergic rhinitis in adults and kids 5 years and up.

Recent data suggest that 0.1% azelastine nasal spray may prevent 1 COVID-19 infection in about every 23 adults compared to placebo.

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