Watch for TMP/SMX Rxs for Patients on Potassium-Boosting Meds

January 2015

You'll hear more about possible harm when TMP/SMX (Bactrim, etc) is combined with meds that increase potassium (ACEIs, spironolactone, etc).

This interaction is more risky than previously thought...and is popping up on more drug interaction software.

Trimethoprim decreases urinary excretion of potassium.

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Table of Contents

Cardiology Suggest Saving Ezetimibe as an Add-On in High-Risk Patients
Interactions Watch for TMP/SMX Rxs for Patients on Potassium-Boosting Meds
Generics Encourage Rxs for "Methylphenidate Extended-Release" Instead of Concerta
Bipolar Disorder Don't Suggest Aripiprazole or Ziprasidone for Bipolar Depression
Hypothyroidism Explain That Full Benefit of Levothyroxine May Take 6 Months
Diabetes Suggest the Shortest and Thinnest Insulin Needle Available
COPD Watch for Mix-Ups Between Spiriva Respimat and Handihaler
Practice Keep a List of High-Risk Meds at Drop-Off
Eye Health Help Dry-Eye Patients Avoid Topical Vasoconstrictors
Antithrombotics Don't Recommend Newer Oral Anticoagulants for VTEs During Pregnancy
Med Administration Recommend a Different Head Position to Make Swallowing Pills Easier
Pediatrics Use Supportive Care Instead of Meds for Bronchiolitis in Kids