Clarify the Role of Paxlovid or Molnupiravir for COVID-19

New oral antivirals will raise questions about treating COVID-19.

Use Paxlovid (nirmatrelvir/ritonavir) first-line for most outpatients with mild to moderate COVID-19, since it seems more effective...and molnupiravir when other options aren’t available.

Eligibility. Consider these meds for patients with a positive COVID-19 test who are at high risk of developing severe illness (age 65 or older, diabetes, etc)...regardless of vaccination status.