recent gentamicin recalls and shortages are part of a bigger problem related to endotoxin reactions

The recent gentamicin recalls and shortages are part of a bigger problem related to endotoxin reactions.

Patients who get too much endotoxin from IV solutions get fever...shaking chills...dyspnea...and hypotension.

USP sets limits for endotoxin in parenteral antibiotics...but the limit for gentamicin is based on Q8H or Q12H dosing.

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