Consider Cardiovascular Benefits When Recommending Metformin Add-ons
Cardiovascular impact will be considered more when choosing drugs to add to metformin.
We're used to suggesting diabetes meds based on their A1C lowering, side effects, cost, etc. But now CV impact will also be important.
In fact, the SGLT2 inhibitor Jardiance (empagliflozin) is poised to become the first diabetes med approved for reducing CV death in patients with type 2 diabetes and CV disease. It prevents CV death in one in 45 patients over 3 years...and overall mortality in one in 39 patients.