Watch for Andexxa, a New Anticoagulant Reversal Agent

Andexxa (an-DEK-sah, inactivated recombinant factor Xa) will be a new, IV direct oral anticoagulant (DOAC) reversal agent.

Until now, the only reversal agent for the DOACs was Praxbind (idarucizumab). But it only reverses Pradaxa (dabigatran)...a direct thrombin inhibitor.

Andexxa will be bigger news...it's an antidote for two factor Xa inhibitors, Eliquis (apixaban) or Xarelto (rivaroxaban).

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