Rezulin (troglitazone) is now approved for INITIAL therapy of type 2 diabetes
Rezulin (troglitazone) is now approved for INITIAL therapy of type 2 diabetes...and for use with a sulfonylurea. Initially, it was approved only for patients poorly controlled on insulin.
For initial therapy, Rezulin works about as well as metformin (Glucophage) or a sulfonylurea. It lowers blood sugar about 50 mg/dL...and reduces glycosylated hemoglobin (HbA1c) about 1.5%.
Rezulin helps lower insulin resistance. It also seems to improve blood pressure and lipids.